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Research

Department of Psychological Medicine

The Department of Psychological Medicine is the largest department of child mental health in NSW and supports a progressively expanding research base. All clinicians in Psychological Medicine are encouraged to maintain an area of research interest. The strength of the research is the close interface with clinicians and clinical need. There are a variety of active research projects underway in the Department which encompass several topic areas. These include:

  • Eating Disorders
  • Somatoform disorders
  • Shaken Baby Prevention project
  • Developmental Psychiatry
  • Anxiety Disorders Clinic
  • Early-onset psychosis
  • Deafness Clinic
  • Telepsychiatry
  • Liver Transplant

The Department of Psychological Medicine is affiliated with the University of Sydney through the Disciplines of Psychological Medicine, Paediatrics and Child Health and the School of Psychology. Research collaborations also exist with other health and allied health departments within and outside CHW.

School Link Publications

Research Brochures

Eating Disorders

The Eating Disorders Research Group is focussed on the treatment of eating disorders in children and adolescents. Current research includes:

  • Does inpatient weight restoration prior to outpatient family therapy improve outcomes in adolescent anorexia nervosa? A randomised control trial (NHMRC Research Grant, $528,000)
  • Does Hospital-Based Weight Restoration Prior to Outpatient Family Therapy Improve Outcomes for Child and Adolescent Anorexia Nervosa? A Retrospective Investigation of Current Treatment Outcomes Prior to a Proposed Randomised Control Trial.
  • Family-Based Treatment for Young People Treated with Anorexia Nervosa: An Investigation of family Functioning and Relationship Change
  • Validation of EDRCT measures RCADS
  • Retrospective review of impact of discharge weight on outcome of family therapy for AN
  • Emotional responses to food and neurobiological response in children and adults
  • The incidence of early onset eating disorders (APSU study)
  • Eating Disorders and Boys
  • Imaging study: Impact of body image in An (CADE group)- molecular gentic analysis of blood samples
  • Taking a LEAP forward in the treatment of Anorexia Nervosa: a randomized controlled trial
  • Body Image
  • Weight restored inpatients at discharge- Qualitative Interviews
  • Conducting a genome wide association scan for Anorexia Nervosa: A pilot study
  • Metabolism- Adelaide & CHW- insertion of NG tube if not present
  • Garvin PYY
  • A narrative enquiry of recovery in chronic anorexia nervosa
  • Family meal
  • Family interactions and mealtime strategies during the family meal
  • Impact of AN_ Analysis of first session
  • iPad application development
  • Refeeding In AN

Current Research with School of Psychology, University of Sydney

Research team

  • Dr Sloane Madden, Child and Adolescent Psychiatrist, Psych Med, CHW
  • Dr Michael Kohn, Paediatrician, AMU, CHW
  • Dr Simon Clark, Paediatrician, Westmead Hospital
  • Ms Jane Miskovic, Research Psychologist, CHW
  • Mr Andrew Wallis, Senior Social Worker, AMU, CHW

Research facilities are located in the Department of Psychological Medicine, CHW

Research support for group

2010-2014 NHMRC Project Grant (634922) - $557,100.00
Hay P, Touyz S, Meyer C, Madden S, Pike K, Crosby R. Taking a LEAP forward in the treatment of Anorexia Nervosa: a randomized controlled trial

2007-2010 NHMRC Project Grant (457235) - $528,000.00
Touyz S, Lock J, LeGrange D, Madden S, Kohn M, Rhodes P. Does inpatient weight restoration prior to outpatient family therapy improve outcomes in adolescent anorexia nervosa?

Collaborations

  • The University of Sydney - School of Psychology
  • The University of Western Sydney - School of Medicine, School of Education
  • The University of Kiel
  • The Garvan Institute
  • Westmead Hospital
  • The Department of Adolescent Medicine
  • The Department of Gastroenterology

Publications

  1. Kohn, Mi.; Madden, S.; Clarke, S. (2011). Refeeding in anorexia: increased safety and efficiency through understanding the pathophysiology of protein calorie malnutrition. Current Opinion in Pediatrics: 23 (4), 390-394
  2. Ellison, R., Rhodes, P., Madden, S., Miskovic, J., Wallis, A., Baillie, A., Kohn, M. and Touyz, S. (2012), Do the components of manualized family-based treatment for anorexia nervosa predict weight gain?. Int. J. Eat. Disord., 45: 609-614.
  3. Hatch A, Madden S, Kohn M, Clarke S, Touyz S, Gordon E, Williams L. Emotion brain alterations in Anorexia Nervosa: A candidate biological marker and implications for treatment. Journal of Psychiatry and Neuroscience. 2010;35(4):267-74.
  4. Bravender T, Bryant-Waugh R, Herzog D, Katzman D, Kriepe R, Lask B, LeGrange D, Lock J, Marcus MD, Madden S, Nicholls D, O'Toole J, Pinhas L, Rome E, Sokol-Berger M, Wallin U, Zucker N. Classification of Eating Disturbance in Children and Adolescents: Proposed Changes for DSM-V. European Eating Disorder Review. 2010;18(2):79-89.
  5. Hatch A, Madden S, Kohn M, Clarke S, Touyz S, Gordon E, Williams L. EEG in adolescent anorexia nervosa: Impact of refeeding and weight gain. International Journal of Eating Disorders. E-Pub Jan 2010.
  6. Hatch A, Madden S, Kohn M, Clarke S, Touyz S, Williams L. Anorexia Nervosa: Towards an integrative neuroscience model. European Eating Disorder Review. 2010;18:165-79.
  7. Hatch A, Madden S, Kohn M, Clarke S, Touyz S, Gordon E, Williams L. In adolescent Anorexia Nervosa, do cognitive markers of underweight states change with weight gain following a re-feeding intervention? Evidence for a state-trait dissociation. International Journal of Eating Disorders. 2010;43(4):295-306.
  8. Madden S, Morris A, Zurynski Y, Kohn M, Elliot E. The burden of eating disorders in children aged 5 - 13 years in Australia. Medical Journal of Australia. 2009;190(8)410-6.
  9. Rhodes P, Madden S, Brown J. The Maudsley Model of Family-Based Treatment of Anorexia Nervosa: A Qualitative Evaluation of Parent to Parent Consultation. Journal of Marital and Family Therapy. 2009;35(2)181-92.
  10. Haas V, Kohn M. Clarke S, Allen J, Madden S, Muller M, Gaskin K. Body composition changes in females with anorexia. American Journal of Clinical Nutrition 2009;89(4)1005-10.
  11. Rhodes P, Prunty M, Madden S. Life-Threatening Food Refusal in Two Nine-Year Old Girls: Re-Thinking the Maudsley Model. Clinical Child Psychology and Psychiatry. 2009;(14(1):40-51.
  12. Rhodes P, Baillie A, Brown J, Madden S. Can Parent to Parent Consultation Improve the Effectiveness of the Maudsley Model of Family-Based Treatment for Anorexia Nervosa: A Randomized Control Trial. Journal of Family Therapy 2008;30(1):96-108.
  13. Honey A, Boughtwood D, Clarke S, Halse C, Kohn M, Madden S. Support for Parents of Children with Anorexia: What Parents Want. The Journal of Treatment and Prevention 2008;16(1)40-51.
  14. Bravender T, Bryant-Waugh R, Herzog D, Katzman D, Kriepe R, Lask B, LeGrange D, Lock J, Marcus MD, Madden S, Nicholls D, O'Toole J, Pinhas L, Rome E, Sokol-Berger M, Wallin U, Zucker N. Workgroup for Classification of Eating Disorders in Children and Adolescents. Classification of Child and Adolescent Eating Disturbances. Workgroup for Classification of Eating Disorders in Children and Adolescents (WCEDCA). International Journal of Eating Disorders 2007;40(suppl):S117-22.
  15. Wallis A, Rhodes P, Kohn M, Madden S. Five years of family based treatment for anorexia nervosa: The Maudsley Model at the Children's Hospital at Westmead. International Journal of Adolescent Medicine Health 2007;19(3):277-83.
  16. Kohn M, Madden S. Re: critical appraisal of the management of severe malnutrition (letter). Journal of Paediatrics & Child Health 2007;43(4):320.
  17. Haas VK, Allen JR, Kohn MR, Clarke SD, Zhang S, Briody JN, Gruca M, Madden S, Muller MJ, Gaskin KJ. Total body protein in healthy adolescent girls: validation of estimates derived from simpler measures with neutron activation analysis. American Journal of Clinical Nutrition 2007;85(1):66-72.
  18. Stone M, Briody J, Kohn M, Clarke S, Madden S, Cowell CT. Bone changes in adolescent girls with anorexia nervosa. Journal of Adolescent Health 2006;39(6):835-41.
  19. Honey A, Clarke S, Halse C, Kohn M, Madden S. The Influence of Siblings on the Experience of Anorexia Nervosa for Adolescent Girls. European Eating Disorders Review 2006;14(5):315-22.
  20. Rhodes P, Baillee A, Brown J, Madden S. Parental efficacy in the family-based treatment of anorexia: Preliminary Development of the Parents Versus Anorexia Scale (PVA). European Eating Disorders Review 2005;13(6):399-405.
  21. Rhodes P, Gosbee M, Madden S, Brown J. Communities of concern in the family-based treatment of anorexia nervosa, towards a consensus in the Maudsley model. European Eating Disorders Review 2005;13(6):392-8.
  22. Bornholt L, Brake N, Thomas S, Russell L, Madden S, Anderson G, Kohn M, Clarke S. Understanding Affective and cognitive self evaluations about the body for adolescent girls. British Journal of Health Psychology 2005;10(4):485-503.
  23. Halse C, Boughtwood D, Clarke S, Honey A, Kohn M, Madden S. The illusion of food: multiple meanings of nasogastric tube feeding in the treatment of anorexia nervosa. European Eating Disorders Review 2005;13(4):264-72.
  24. Madden S. The management of anxiety disorders in children and adolescents. Medicine Today 2005;6(5):14-20.
  25. Rhodes P, Madden S. Scientist-practitioner family therapists, post-modern medical practitioners and expert parents: second-order change in the eating disorders program, at The Children's Hospital at Westmead. The Journal of Family Therapy 2005;27(2):171-82.
  26. Madden S. "Anorexia nervosa" - still relevant in the twenty-first century? A review of William Gull's anorexia nervosa. Clinical Child Psychology and Psychiatry 2004;9(1):149-54.

Books and Chapters

  1. Wallis A, Rhodes P, Kohn M, Madden S. The family based treatment of anorexia nervosa at Children's Hospital, Westmead: Implementation, experience and practice challenges. In Bennett D, Towns S, Elliot E, Merrick J, editors, Challenges in Adolescent Health: An Australian Perspective. Hauppauge, NY; Nova Science Publishers 2009.
  2. Madden S. Evidence-informed care of children with eating disorders. In Fornari V, Dancyger I, editors. Evidence Based Treatment for Eating Disorders: Children, Adolescents and Adults. New York, NY; Nova Science Publishers 2009.
  3. Kohn M, Madden S, Clarke S, Andersen G. Inpatient treatment issues for children and adolescents with eating disorders. In Hay P, Paxton S, editors. Treatment Approaches for Body Dissatisfaction and Eating Disorders: Evidence into Practice. Melbourne; IP Communications 2009.
  4. Boris N, Clarke S, Evans J, LeGrange D, Kohn M, Lelwica M, Lock J, Madden S, Rich E, Touyz S, international advisory panel. In Halse C, Honey A, Boughtwood D. Inside Anorexia: The Experiences of Girls and Their Families.London: Jessica Kingsley Publishers 2008.
  5. Nunn KP, Dey C, Lonworth J, Hazell P, Madden S, Starling J, Dossetor D, Riordan D, Wiltshire C, editors. The Clinician's Guide to Psychotropic Prescribing in Children and Adolescents. Sydney: Child and Adolescent Mental Health Statewide Network 2003.
  6. Madden S, Dey C, English M, Nunn K. A practical guide to emergency medicine. In Nunn KP, Dey C, editors. The Clinician's Guide to Psychotropic Prescribing in Children and Adolescents. Sydney: Child and Adolescent Mental Health Statewide Network 2003:94-114.
  7. Madden S. Anxiety Disorders. In Nunn KP, Dey C, editors. The Clinician's Guide to Psychotropic Prescribing in Children and Adolescents. Sydney: Child and Adolescent Mental Health Statewide Network 2003:140-50.
  8. Madden S. Depression. In Nunn KP, Dey C, editors. The Clinician's Guide to Psychotropic Prescribing in Children and Adolescents. Sydney: Child and Adolescent Mental Health Statewide Network 2003:184-90.
  9. Madden S, Dey C, Nunn K. Substance abuse and dependency. In Nunn KP, Dey C, editors. The Clinician's Guide to Psychotropic Prescribing in Children and Adolescents. Sydney: Child and Adolescent Mental Health Statewide Network 2003:219-31.

Published Abstracts

  1. Ellison R, Madden S, Kohn M, Rhodes P, Touyz S, Miskovic J, Wallis A. Mechanisms of change in the Maudsley model of family-based treatment for anorexia nervosa. Proceedings of the International Conference of Eating Disorders, Salzburg, Austria, June 10-12, 2010. p41.
  2. Madden S, Kohn M, LeGrange D, Touyz S, Miskovic J, Rhodes P. A RCT of inpatient treatment in adolescent anorexia nervosa. Proceedings of the International Conference of Eating Disorders, Salzburg, Austria, June 10-12, 2010. p340.
  3. Madden S, Nicholls D, Pinhas L, Katzman D. Early onset eating disorder in boys, a prospective study. Proceedings of the International Conference of Eating Disorders, Salzburg, Austria, June 10-12, 2010. p34.
  4. Miskovic J, Madden S, Wallis A, Rhodes P, Kohn M, Touyz S. Waiting for weight gain: an eight-year ase review of the role of hospitalisation and family based treatment in weight recovery from adolescent anorexia nervosa. Proceedings of the International Conference of Eating Disorders, Salzburg, Austria, June 10-12, 2010. p32.
  5. Madden S, Miskovic J, Touyz S, Kohn M, Rhodes P, Wallis A, Clarke S. Does hospital-based weight restoration prior to outpatient family therapy improve outcomes for young people treated for anorexia nervosa. 15th Annual Meeting, Eating Disorder Research Society, Brooklyn, New York, USA, September 24-26, 2009, p. 163.
  6. Wallis A, Rhodes P, Madden S, Kohn M. Five years of family based treatment for anorexia nervosa: The Maudsley Model at the Children's Hospital at Westmead. The 6th Annual Conference, Australia and New Zealand Academy of Eating Disorders, Perth, Australia, August 29-30, 2008. p.38.
  7. Hatch A, Madden S, Kohn M, Clarke S, Touyz S, Williams L. Anorexia Nervosa: Towards and integrative neuroscience model. The 6th Annual Conference, Australia and New Zealand Academy of Eating Disorders, Perth, Australia, August 29-30, 2008. p.57.
  8. Madden S. The Neurobiology of Eating Disorders: A Path to the Future or Just More Pretty Pictures? 5th Annual Conference, Australia and New Zealand Academy of Eating Disorders, Melbourne, Australia, August 28-30, 2007: p. 40.
  9. Haas V, Kohn MR, Gaskin K, Clarke S, Allen J, Madden S, Lochs H, Müller MJ. Protein status of adolescent patients with Anorexia Nervosa. Clinical Nutrition 2007,2(S2):13
  10. Haas V, Kohn M, Müller M, Clarke S, Madden S, Lochs H, Gaskin K. Cortisol as a mediator of central fat accumulation in anorectic patients during weight gain . The 89th Annual Meeting of the Endocrine Society Toronto, June 2 - 5, 2007 Number 852879
  11. Touyz S, Hay P, Madden S. International Forum: Breaking new frontiers in research into eating disorders: exciting new data form the Antipodes. Eating Disorders 2007. The 8th London International Eating Disorders Conference. London March 29-31, 2007, p. 38-39.
  12. Madden S, Kohn M. Changes in brain gray and white matter in adolescent females with anorexia nervosa following refeeding using volumetric MRI. Neuropsychiatric Disease and Treatment 2006;2(3)S52.
  13. Hatch A, Madden S, Kohn M, Clarke S, Touyz S. Emotion processing in adolescent anorexia nervosa: integrating behavioral and brain function measures. Neuropsychiatric Disease and Treatment 2006;2(3)S53.
  14. Madden S. Neuroimaging and eating disorders: What options for the future? Eating Disorder Research Society Annual Meeting, Port Douglas, Australia, August 31 - September 2, 2006: p. 27.
  15. Madden S, Kohn M. Changes in brain gray and white matter in adolescent females with anorexia nervosa following refeeding using volumetric MRI. Proceedings of the International Conference on Eating Disorders, Barcelona, Spain, June 7-10, 2006: p. 7.
  16. Haas V, Kohn M, Madden S. Body protein repletion during weight recovery in anorexia nervosa. Proceedings of the International Conference on Eating Disorders, Barcelona, Spain, June 7-10, 2006: p. 35.
  17. Haas V, Kohn M, Madden S, Clarke S, Mueller M. Body Composition, metabolism and endocrine function in anorexia nervosa. Australian and New Zealand Academy of Eating Disorders Annual Conference, Sydney, Australia, August 25-27, 2005: p. 31.
  18. McDermott B, Madden S. Nasogastric feeding and adolescent anorexia nervosa: the whys and wherefores. Australian and New Zealand Journal of Psychiatry 2005;39(1):A133.
  19. Madden S, Wallis A, Rhodes P, Le T, Kohn M. The implementation and clinical outcomes of manualised family therapy at the Children's Hospital at Westmead and Westmead Hospital Australia. Proceedings of the International Conference on Eating Disorders, Montreal, Canada, April 27-30, 2005:53-54.
  20. Madden S, Boughtwood D, Clarke S, Halse C, Honey A, Kohn M. The illusion of food: multiple meanings of nasogastric tube feeding in the treatment of anorexia nervosa. 7th London International Conference on Eating Disorders, London, April 4-6, 2005: p. 60.
  21. Madden S, Byrne S. An Observational Study of Patients Admitted to The Eating Disorder Unit at The Children's Hospital at Westmead between July 1997 and March 2004. 7th London International Conference on Eating Disorders, London, April 4-6, 2005:86-7.
  22. Madden S, Wallis A, Rhodes P, Le T, Kohn M. The Implementation and Clinical Outcomes of Manualised Family Therapy at the Children's Hospital at Westmead, Australia. Proceedings of The Academy of Eating Disorders International Conference on Eating Disorders P 53-54 2005.
  23. Halse C, Boughtwood D, Clarke S, Honey A, Kohn M, Madden S. The illusion of food: multiple meanings of nasogastric tube feeding in the treatment of anorexia nervosa. Australian and New Zealand Academy of Eating Disorders Annual Conference, Melbourne, Australia, August 27-8, 2004: p. 35.
  24. Honey A, Halse C, Clarke S, Kohn M, Madden S. Coping with anorexia: What strategies do parents use? Australian and New Zealand Academy of Eating Disorders Annual Conference, Melbourne, Australia, August 27-8, 2004: p. 46.
  25. Trinh Ha M, Halse C, Marsh H, Clarke S, Kohn M, Madden S. Australian Adolescents with Eating Disorders. Australian and New Zealand Academy of Eating Disorders Annual Conference, Melbourne, Australia, August 27-8, 2004: p. 50.
  26. Trinh Ha M, Clarke S, Halse C, Kohn M, Madden S, Marsh H. The changing profile of anorexia in Australia. Third International Biennial SELF Research Conference, Berlin, Germany, July 4-7, 2004, p. 108.
  27. Kohn M, Madden S, Clarke S. Conundrums in dealing with adolescents with anorexia: tube feeding, guardianship orders and sedation. Asian Pacific Eating Disorders Congress, Melbourne, Australia, November 10-14, 2002.

Somatoform Disorders

Current research projects:

  • Emotional processing in children with medically unexplained symptoms

Research team

  • Dr Kasia Kozlowska
  • Prof. Lea Williams
  • Dr. Kerri Brown
  • Dr. Loyola McClean
  • Dr. Donna Rose
  • Dr. Angelika Claussen
  • Ms Helen Doan
  • Ms Samantha Soe
  • Dr. Deepak Gill
  • Dr Fiona Davies
  • Ms Blanche Savage
  • Dr Catherine Chudleigh
  • Ms Sue Foley
  • Ms Margaret English

Collaborations

Department of Neurology, CHW
The Brain Dynamics Centre, Westmead Hospital

Publications

  1. Kozlowska, K. , Williams, L.M. (2010). Self-protective organization in children with conversion symptoms. A cross-Sectional Study Looking at Psychological and Biological Correlates. Mind & Brain, The Journal of Psychiatry 1, 43-57.
  2. Kozlowska, K. (2009). Attachment relationships shape pain-signaling behavior. Journal of Pain 10, 1020-1028.
  3. Kozlowska, K. , Williams, L.M. (2009). Self-protective organization in children with conversion and somatoform disorders. Journal of Psychosomatic Research 67, 223-233.
  4. Kozlowska, K. (2007). The developmental origins of conversion disorder. Clinical Child Psychology and Psychiatry, 6, 575-591.
  5. Ciarrochi, J., Heaven, P.C.L., & Davies, F. (2007). The impact of hope, self-esteem, and attributional style on adolescents' school grades and emotional well-being: A longitudinal study. Journal of Research in Personality, 41, 1161-1178.
  6. Kozlowska, K. (2005). Healing the Disembodied Mind. Contemporary models of Conversion Disorder. Harvard Review of Psychiatry 13, 1-13.

Research support:

Prof. Williams fellowship grant

Somatoform and Attachment Case Studies

Publications

  1. Kozlowska K, Foley S, Savage B. (in press) Fabricated Illness: working within the family system to find a pathway to health Family Process.
  2. Kozlowska K, Khan R. (2011). A developmental, body-oriented intervention for children and adolescents with medically unexplained chronic pain. Clinical Child Psychology and Psychiatry.
  3. Minshall GA, Davies F, Baur LA. (2011) Behavioral management of pediatric obesity. In: Ferry RJ Jr (Ed). Management of Pediatric Obesity and Diabetes. 1st edition. New York: Humana Press.
  4. Dale, R.C., Singh, H., Troedson, C., Pillai, S., Gaikiwari, S., Kozlowska, K. (2010). A prospective study of acute movement disorders in children. Developmental Medicine and Child Neurology.
  5. Davies F, Baur LA. Treating obesity in childhood: behavioural considerations. (2009) In: VR Preedy, ed. International Handbook of Behavior, Diet and Nutrition. Springer Press: London.
  6. Kozlowska, K., Rose, D., Khan, K., Kram, S., Collins, J. (2008). A Conceptual Model and Practice Framework for the Management of Chronic Pain in Children and Adolescents. Harvard Review of Psychiatry, 16, 136-150.
  7. Davies, F., Deane, F. P., & Dalley, A. (2006). General practitioners help seeking intentions for mental health problems. Australian Journal of Primary Health, 12,66-71.

Child Protection: Shaken Baby Prevention Project

The Shaken Baby Prevention Project is a collaborative project between CHW Psychological Medicine, Child Protection Unit and Brain Injury Rehabilitation Unit and Westmead Hospital Social Work Department. It has involved development of a video for parents to prevent child abuse in the form of shaking babies. The video depicts how parents can respond to a crying baby in a safe way. It is being used or has influenced the development of projects in community health, hospitals and universities around the world. There are now 12 language versions of the video being used in Western Sydney and internationally. Twelve thousand copies of the video were bought by the previous Sydney West Area Health Service during 2011 via Kids Health. There is active collaboration with projects in Greece, Poland, the U.K., Hungary, Israel, Japan, Malaysia, Brazil and Argentina.

Research team

  • Ms Sue Foley, Senior Social Worker, Psych Med, CHW
  • Dr Kasia Kozlowska, Psych Med, CHW

Research facilities are located in the Department of Psychological Medicine, CHW

Collaborations

  • Child Protection Unit, CHW
  • Child Protection Unit, SCH

Publications

  1. Kozlowska, K., Scher, C., Williams, L. (2011). Patterns of Emotional-Cognitive Functioning in Pediatric Conversion, Patients: Implications for the Conceptualization of Conversion Disorders, Psychomatic Medicine, 73(9), 775-788.
  2. Tolliday, F., Simons, M., Foley, S., Benson, S., Stephens, A., Rose D. (2010) Inspiration to Action: The Shaken Baby Prevention Project in Western Sydney. Communities, Children and Families Australia, 5.
  3. Kozlowska, K., Foley, S. and Crittenden, P.M. (2006) Factitious Illness by Proxy: understanding underlying psychological processes and motivations. Special Attachment issue. Australian and New Zealand Journal of Family Therapy
  4. Kozlowska, K. and Foley, S. (2006) Attachment and Risk of future harm - a case of non-accidental brain injury. Special Attachment issue. Australian and New Zealand Journal of Family Therapy

2009, Media Release CHW Children and Inflicted Traumatic Brain Injury

Report in CHW Annual Report 2010

On ARCHI website: http://www.archi.net.au/resources/workforce/nursing/shaking-baby

Report in AASW newsletter: http://www.aasw.asn.au/document/item/789

Developmental Psychiatry

The Developmental Psychiatry Research group is focused on furthering the understanding of children with developmental disability and mental health problems. Current research studies include:

  • Emotion-based Social Skills Training in Schools which aims to train 64 DET school counsellors as EBSST group facilitators and evaluate the effectiveness of EBSST in promoting emotional and social skills and preventing mental health problems in over 300 students with Autism and Asperger's Syndrome by comparing wait-list and treatment groups.
  • Emotion-based Social Skills Training for Moderate and Severe Intellectual Disability aims to modify EBSST for children with moderate and severe intellectual disability and evaluate its effectiveness in promoting emotional and social skills and preventing mental health problems.
  • Training and Curriculum Project which aims to provide training to clinicians in mental health in Intellectual Disability and evaluate clinicians' skill, knowledge, confidence, and collaboration after completing training.
  • Stepping Stones Triple P Project which aims to deliver group Stepping Stones Triple P intervention across four Schools for Specific Purposes and evaluate program effectiveness in reducing children's challenging behaviours, improving parental mental health and marital relationships.
  • SSRI Trial in Autism which aims to evaluate the effectiveness of SSRIs in the treatment of children with Autism.
  • Randomised Controlled Trial of Emotion-based Social Skills Training for Children with High-Functioning Autism and Aspergers Syndrome which aims to evaluate a training curriculum for children and their parents to develop emotional and social skills thus enhancing children's resilience to developing psychopathology in later life;
  • Pilot Study of Emotion-based Social Skills Training for Children with Autism and Intellectual Disability which aims to develop a training curriculum for children and their parents to develop emotional and social skills thus enhancing children's resilience to developing psychopathology in later life;
  • Loneliness, Friendships and Depression in High Functioning Autism and Aspergers Syndrome which aims to determine the correlates of depression in children and gain an understanding of the experience of friendships in children with high functioning autism and Aspergers Syndrome.

Research team

  • Dr Michelle Wong, Clinical Psychologist, BSc(Psychol), D(Clin Psych), PhD, MAPS
  • Dr David Dossetor, Child Psychiatrist, MA, MBBChir, DCH, RRCP, FRCPsych, MD
  • Dr Sandra Heriot, Clinical Psychologist, MA(Hons), PGDipAppPsyc, PhD, MAPS
  • Ms Sandy Vickerstaff, Psychologist, BA(Hons)
  • Dr Victoria Grahame, Clinical Psychologist, BSc(Hons)Psych, MSc(Psych), D(ClinPsyc)
  • Ms Belinda Ratcliffe, Psychologist, BSc(Psych)
  • Ms Louisa Carroll, Clinical Psychologist
  • Ms Lisa Brice, Clinical Psychologist
  • Dr Phil Ray, Clinical Psychologist

Research facilities are located in the Department of Psychological Medicine, CHW.

Publications

  1. Vickerstaff, S., Heriot, S., Wong M.G., Lopes A., & Dossetor, D. (2007). Intellectual ability, self-perceived social competence and depressive symptomatology in children with high-functioning Autistic Spectrum Disorders. Journal of Autism and Developmental Disorders, 37(9), 1647-1664.
  2. Wong, M.G., & Heriot, S.A. (2008). Parents of children with cystic fibrosis: How they hope, cope and despair. Child: Care, Health and Development, 34(3), 344-354.
  3. Wong, M.G., & Heriot, S.A. (2007). Vicarious futurity in autism and childhood dementia. Journal of Autism and Developmental Disorders, 37(10), 1833-1841.
  4. Lopes A., Wong, M.G., Heriot, S., Vickerstaff, S., & Dossetor, D. (2006). Pilot evaluation of the emotion-based social skills training program for children with developmental disabilities. Australian Journal of Psychology: Combined Abstracts of 2006 Australian Psychology Conferences, 58(s2006), 158.
  5. Vickerstaff, S., Heriot, S., Wong M., Lopes A., & Dossetor, D. (2006). Intellectual ability, self-perceived social competence and depressive symptomatology in children with high-functioning Autistic Spectrum Disorders. Australian Journal of Psychology: Combined Abstracts of 2006 Australian PsychologyConferences, 58(s2006), 202.
  6. Wong, M.G. (2006). Teaching social skills and anxiety management in children with Autistic Spectrum Disorders. The Clinician, 3, 127-133.
  7. Wong, M., Heriot, S., Lopes A., Vickerstaff, S., & Dossetor, D. (2006). Development of an emotion-based social skills training program for children with developmental disabilities. Australian Journal of Psychology: Combined Abstracts of 2006 Australian Psychology Conferences, 58(s2006), 209.
  8. Wong, M.G. (2005). The 3di - A reliable and valid tool for the diagnosis of autism spectrum disorders? @CAPTOS, 1, 7.

Collaborations

  • School of Psychology, University of Sydney
  • Statewide Behaviour Intervention Service, Department of Ageing, Disability and Home Care
  • Department of Education and Training

Research support for group (2008-2010)

  • 2008-2009: $220 000, Mental Health Enhancements funding, MHDAO
  • 2010: $29 000, Collier Foundation

Anxiety Disorders Clinic

The Anxiety Clinic is a specialised training and research clinic run by the Department of Psychological Medicine, CHW, in conjunction with students from the Doctor of Clinical Psychology Program at the University of Sydney. The purpose of the Clinic is to provide psychological treatment for children and adolescents with anxiety problems. Current research being conducted through the clinic includes:

  • Efficacy of acceptance-mindfulness therapy in children with anxiety: a controlled trial. The overall aim is to evaluate the efficacy of acceptance and commitment therapy (including mindfulness- hereby known as ACT) integrated with CBT in treating children with anxiety disorders. Specific objectives are to
    • Compare the psychological outcomes of three treatment groups: a) standard treatment (Cognitive Behavioural Therapy- CBT) b) ACT integrated with CBT- hereby known as ACT/CBT c) waiting list no-treatment control group
    • Determine whether there are any patient demographic or clinical characteristics related to treatment outcomes.
  • A randomised controlled trial of Acceptance and Commitment Therapy for anxious adolescents: Effectiveness and mechanisms for change. This is a sub-arm of the above study (PhD- Ms Jessica Swain) focusing on adolescents and underlying processes that are related to improvements in clinical outcomes. For example, the study will investigate whether processes such as use of acceptance are predictive of improvements in quality of life.
  • Recruitment will cease at the end of 2012 by which time 165 participants (86 children and 81 adolescents) will have completed treatment.

Research team

CI:

  • Dr Karen Hancock, Senior Research Psychologist, Psych Med, CHW

AI's:

  • Dr Angela Dixon, Senior Clinical Psychologist, Psych Med, CHW
  • Ms Siew Koo, Clinical Psychologist, Psych Med, CHW
  • Ms Karen Munro, Senior Clinical Psychologist, Psych Med, CHW
  • Ms Cassandra Hainsworth, Research Psychologist, Psych Med, CHW
  • Ms Jessica Swain, PhD Candidate, Macquarie University

Research facilities are located in the Department of Psychological Medicine, CHW

Collaborations

  • The Centre for Emotional Health, Macquarie University
  • PEIRS-CAMHS
  • Clinical Psychology Unit, University of Sydney

Publications

  1. Hancock, K., & Koo, S. (2010). Cool-Mind for Kids: Workbook. Children's Hospital at Westmead.
  2. Hancock, K., & Koo, S. (2010). Cool-Mind for Kids: Parent companion. Children's Hospital at Westmead.
  3. Hancock, K., & Koo, S. Mind-Chill (2010): Workbook. A program for young people with worries. Workbook. Children's Hospital at Westmead.
  4. Hancock, K., & Koo, S. Mind-Chill (2010): Workbook. A program for young people with worries. Workbook. Children's Hospital at Westmead
  5. Hancock, K., & Koo, S. Cool-Mind (2010). Therapist manual. Children's Hospital at Westmead.
  6. Swain J, Hancock K,, Dixon A, Koo S,, Bowman J. (submitted). Study protocol: A randomised controlled trial of Acceptance and Commitment Therapy for anxious children and adolescents, BMC Psychiatry
  7. van der Meer, M., Dixon, A., & Rose, D. (2008). Parent and child agreement on reports of problem behaviour obtained from a screening questionnaire, the SDQ. European Journal of Child and Adolescent Psychiatry.
  8. Dixon, A., Howie, P., & Starling, J. (2005). Trauma exposure, posttraumatic stress and psychiatric comorbidity in female juvenile offenders. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 798-806.
  9. Dixon, A., Howie, P., & Starling, J. (2004). Psychopathology in female juvenile offenders. Journal of Child Psychology and Psychiatry and Allied Disciplines, 45, 1150-1158.
  10. Dixon, A. (2003). "At all costs let us avoid any risk of allowing our hearts to be broken again" A review of John Bowlby's Forty-four juvenile thieves. Journal of Child Clinical Psychology and Psychiatry, 8, 274-283.

Early-onset psychosis

Research team

  • Ms Cassandra Hainsworth, Research Psychologist, Psych Med, CHW
  • Ms Karen Munro, Senior Clinical Psychologist, Psych Med, CHW
  • Dr Angela Dixon, Senior Clinical Psychologist, Psych Med, CHW

Collaborations

  • The Brain Dynamics Centre, Westmead Hospital
  • The University of Sydney

Publications

  1. Starling J, Williams L, Hainsworth C, Harris A. The presentation of early onset psychotic disorders. Australia and New Zealand Journal of psychiatry, in press
  2. Hainsworth C, Starling J, Brand F, Groen K, Munro K. trauma and psychotic symptoms: Data from a pediatric mental health inpatient unit. Journal of traumatic stress. 2011. In press.
  3. de Kloet L, Starling J, Berntsen E, Hainsworth C, Chapman L, Hancock K, Risk factors for self harm in children and adolescents admitted to a mental health inpatient unit. Australasian Psychiatry. 2011. In press.
  4. Berntsen E, Starling J, Durheim E, Hainsworth C, de Kloet L, Chapman L, Hancock K. Temporal trends in self harm and aggression on a paediatric mental health ward. Australasian Psychiatry. 2011; 19(1): 64-69.

Published Abstracts

  1. Hainsworth C, Starling J, Munro K, Groen K, Brand F. Trauma histories in children and adolescents with psychotic symptoms. Schizophrenia Bulletin. 2011; 37(1): 16.
  2. Starling J, Hainsworth C, Harris A W, Hubby A, Williams L. Cognitive impairments in 26 children and adolescents with psychotic disorders compared with normal controls. Schizophrenia Bulletin. 2009; (35):229.
  3. Starling J, Harris A W, Williams L, Smith C, Nagy M: Clinical and cognitive features of early onset psychosis: pilot data from an early psychosis study. Schizophrenia Bulletin. 2009; (35):44.
  4. Hainsworth C, Starling J, Groen K, Brand F: Trauma and psychotic symptoms: results from a paediatric teaching hospital cohort. RANZCP Faculty of Child and Adolescent Psychiatry Annual Conference 2009;

Deafness Clinic

The Deafness Clinic provides multidisciplinary services to children and adolescents who are Deaf/hearing impaired. The Clinic is currently engaged in a pilot study that explores the psychological intervention needs of families of children who have been diagnosed with congenital hearing loss. The outcomes of this study will be used to inform future development of primary psychosocial interventions for Deaf/hearing impaired children and their families. This is a collaborative study between the Deafness Centre and Departments of Audiology and Psychological Medicine at Children's Hospital at Westmead (CHW).

Research team

  • Ms Siew Koo, BBSc, GradDipAppPsych, MPsych (clin.), MAPS, Clinical Psychologist
  • Ms Rosemary Douglas, B.A.M.Aud.S.A (CCP), Head Audiologist, Department of Audiology
  • Dr Elizabeth Peadon, MBBS (Hons), MPH, FRACP, Developmental Paediatrician, Deafness Centre

Research facilities are located in the Department of Psychological Medicine, CHW,

  • Research support for group (2005-2008) Centre for Mental Health, NSW Health Department - recurrent funding - 1FTE clinical psychologist position

Collaborations

Deafness Centre and Departments of Audiology, CHW

Telepsychiatry

The Telepsychiatry Research Team is engaged in ongoing evaluation research of the Child and Adolescent Psychiatry Telemedicine Outreach Service (CAPTOS) service.

Research team

  • Ms Sue Foley, Senior Social Worker, Psych Med, CHW
  • Dr Jean Starling, Child and Adolescent Psychiatrist, Psych Med, CHW

Research facilities are located in the Department of Psychological Medicine, CHW,

Publications

  1. Starling, J. & Foley, S. (2006) From pilot to permanent service: ten years of paediatric telepsychiatry. Journal of Telemedicine and Telecare; 12 (Suppl 3):S3:80-82.
  2. Starling J, Rosina R, Nunn K and Dossetor D. (2003) Child and Adolescent Telepsychiatry in New South Wales: Moving beyond clinical consultation. Australasian Psychiatry;11(Suppl11): S117-S119.
  3. Kopel, H., Nunn, K., & Dossetor, D. (2001) Evaluating satisfaction with a child and adolescent psychological telemedicine outreach service. Journal of Telemedicine and Telecare; 7 (Suppl 2): 35-40.
  4. Dossetor, D., Nunn, K., Fairley, M, & Eggleton, D. (1999) A child and adolescent outreach service for rural New South Wales: A telemedicine pilot study. Journal of Paediatrics and Child Health; 35: 525-529.

Liver Transplant

Current projects

Family risk and resilience in serious paediatric liver disease - PhD project

PTSD in parents of liver transplant recipients.

Research team

  • Dr Michael Bowden
  • Diana Carmody
  • Margaret English
  • Vicki Jermyn
  • Mee Mee Lee
  • Dr Ted O'Loughlin
  • Dr Michael Stormon
  • Dr Kavita Seth

Collaborations

  • Sydney Children's Hospital, Randwick;
  • Royal Children's Hospital Brisbane

Publications

  1. Eapen V, Bowden M. Pediatric Psychosomatic Medicine: Australia. In: Shaw R, DeMaso D (Eds) Textbook of Pediatric Psychosomatic Medicine. American Psychiatric Publishing, Inc., Arlington, 2010.
  2. Bowden MR, Newman L. For the Long Haul (Chronic Illness in Children). Australian Doctor 13 March 2009, pp 41 - 43.
  3. Bowden MR. Out of the Dark (Adolescent Depression). Australian Doctor 03 October 2008, pp 43 - 45.
  4. Bowden MR. School of Hard Knocks (Resilience in Children and Adolescents). Australian Doctor 21 March 2008, pp 33 - 34.
  5. Senediak C, Bowden M. Clinical Supervision in Advanced Training in Child and Adolescent Psychiatry: A Reflective Practice Model. Australasian Psychiatry 2007; 15(4): 276 - 280.

Molecular Psychiatry Laboratory

Head: Ruth Urwin
Email:
RuthU@chw.edu.au

On December 19, 1996, Ruth Urwin and Prof Kenneth Nunn initiated Molecular Psychiatry research at CHW, Westmead. Although Prof Nunn has recently left CHW and is now at John Hunter Hospital in Newcastle, NSW, Ruth and Ken still conduct their research as a scientist-clinician team.

Overall Aim:

To investigate/define biological mechanisms involved in behaviour and psychiatric disorders

Current project aim:

To investigate the molecular genetics of anorexia nervosa

Future aims:

  • To investigate the relationship between genotype and the therapeutic response to specific psychotropic drugs
  • To investigate gene-gene interactions in closely connected biological systems
  • To investigate gene-environment interactions

Potential impact on clinical practice:

Currently, there are few (if any) biological tests available to aid clinical decisions in psychiatry whether it is for diagnosis or treatment. Through our research (which includes collaboration with others) we are working towards providing such tests which should provide a turning point for psychiatric diagnosis and treatment.

Achievements to date:

In 2002, we discovered a novel 343-bp DNA sequence in the promoter region of the norepinephrine transporter gene and showed that anorexia nervosa (restrictive subtype) is associated with a polymorphism in this novel sequence. This discovery resulted in an international press release by Molecular Psychiatry, the journal in which the finding is published. The publication was a highlight of Nature Publishing Group on August 1, 2002 at http://www.nature.com/nature/view/020801.html and the subject of numerous media interviews and press reports including a front page story in the Sydney Morning Herald at http://www.smh.com.au/articles/2002/08/05/1028157909476.html and a recent segment on ABC TV Catalyst ("Anorexia Gene" at http://www.abc.net.au/catalyst/stories/s914473.htm).

Publications (Peer-reviewed original research)

1. Urwin RE, Bennetts BH, Wilcken B, Lampropoulos B, Beumont PJ, Russell JD, Tanner SL, Nunn KP. Gene-gene interaction between the monoamine oxidase A gene and solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2 gene in anorexia nervosa (restrictive subtype). Eur J Hum Genet. 2003; 11: 945-50, advance online publication, 24 September 2003; doi:10.1038/sj.ejhg.5201077 (publication Adobe Acrobat PDF) (European Journal of Human Genetics)

2. Urwin RE, Bennetts BH, Wilcken B, Beumont PJ, Russell JD, Nunn KP. Investigation of epistasis between the serotonin transporter and norepinephrine transporter genes in anorexia nervosa. Neuropsychopharmacology. 2003; 28: 1351-5, advance online publication, 14 May 2003; doi:10.1038/sj.npp.1300204 (publication Adobe Acrobat PDF) (Neuropsychopharmacology)

3. Urwin RE, Bennetts B, Wilcken B, Lampropoulos B, Beumont P, Clarke S, Russell J, Tanner S, Nunn KP. Anorexia nervosa (restrictive subtype) is associated with a polymorphism in the novel norepinephrine transporter gene promoter polymorphic region. Mol Psychiatry. 2002; 7: 652-7. (publication Adobe Acrobat PDF) (Molecular Psychiatry)

PM Research News

This document was updated on Tuesday, 2 April 2013.

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